CALCINEURIN-MODULATED ANTIMICROBIAL PEPTIDE EXPRESSION IS REQUIRED FOR THE DEVELOPMENT OF HELICOVERPA ARMIGERA

Calcineurin-Modulated Antimicrobial Peptide Expression Is Required for the Development of Helicoverpa armigera

Helicoverpa armigera is a universal pest around the world that has been extensively used as a model organism for agricultural pests.Calcineurin (CAN) is an important Ca2+-dependent phosphatase that is participated in various biological pathways.Here, we revealed that CAN inhibition significantly arrested H.armigera larval development by reducing la

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Combination of Crizotinib and Osimertinib in T790M+ EGFR-Mutant Non-Small Cell Lung Cancer with Emerging MET Amplification Post-Osimertinib Progression in a 10-Year Survivor: A Case Report

Tyrosine NUTRI B100 COMPLEX kinase inhibitors (TKIs) represent the standard treatment for patients with non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations.The duration of the response is, however, limited in time owing to the development of resistance mechanisms to both first- and second-generation agents

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AN OPERATING MODEL FOR THE ENVIRONMENTAL RISK ASSESSMENT APPLIED TO ITALIAN SITES OF COMMUNITY IMPORTANCE: IDENTIFICATION OF POTENTIAL EFFECTS ON SOIL

The fast development of agro-biotechnologies asks for a harmonized approach in risk APPLICATOR BOTTLE analysis of GMOs releases.An Italian experts group has elaborated an operating model for the environmental risk assessment (OMERA) based on the assumption that the occurring of a risk is related to the presence of four components: source, diffusion

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